In this study, 9 nm superparamagnetic iron oxide nanoparticles (SPION) were functionalized by\npolyamidoamine (PAMAM) dendrimer. Using tetracholoroauric acid (HAuCl4), magnetodendrimer\n(MD) samples were conjugated by gold nanoparticles (Au-NPs). Two different reducing agents, i.e.\nsodium borohydride and hydrazine sulfate, and pre-synthesized 10-nm Au-NP were used to evaluate\nthe efficiency of conjugation method. The samples were characterized using X-ray diffractometry\n(XRD), transmission electron microscopy (TEM), Fourier transform infrared (FTIR) spectroscopy,\nUV-visible spectroscopy and fluorescence spectroscopy. The results confirmed that Au-\nNPs produced by sodium borohydrate and the pre-synthesized 10-nm Au-NPs were capped by MDs\nwhereas the Au-NP prepared by hydrazine sulfate as a reducing agent was entrapped by MDs.\nOptical properties of the MDs were studied by laser-induced fluorescence spectroscopy (LIF)\nwithin a wide range of visible spectrum. Also, based on the thermal analysis, all synthesized nanostructures\nexhibited a temperature increase using 488 nm and 514 nm wavelengths of a tunable\nargon laser. The new iron oxide-dendrimer-Au NPs synthesized by sodium borohydrate (IDANaBH4)\nproduced the highest temperature increase at 488 nm whereas the other nanostructures\nparticularly pure Au-NPs produced more heating effect at 514 nm. These findings suggest the potential\napplication of these nanocomposites in the field of bioimaging, targeted drug delivery and\ncontrolled hyperthermia.
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